The most common type of oral cancer is squamous cell carcinoma and. Totally fiftyeight fractions were collected from the hydroethanolic leaf extracts of pergularia daemia and terminalia catappa by silica gel column chromatography. Animals pretreated with ethanolic extract of pergularia daemia and standard drug pantaprazole showed very mild lesions and. Greenish yellow or dull white, sweetscented flowers born in axillary, double white corona at the base of a. Pergularia daemia p daemia is one such plant, popularly known as veliparuthi in tamil and utranajutuka in hindi. Table showing the percentage yield of extracts of whole plant of pergularia daemia linn.
Antiinflammatory activity of whole plant of pergularia. Pergularia in world checklist of selected plant families. Asclepediaceae, was extracted with 50% alcohol and a fresh batch of the plant material was successively extracted with petroleum ether, ethyl acetate and nbutanol to determine its diuretic activity. The present study was aimed to investigate the protective role of pergularia daemia ethyl acetate and methanolic extracts pdeae and pdme, respectively. Files are available under licenses specified on their description page. The analgesic activity was studied in mice using hot plate and acetic acid induced writhing methods, while carrageenan induced paw edema was used to access antiinflammatory activity. Analgesic, antiinflammatory and antipyretic activities of. Pergularia daemia is a popular traditional medicine in africa where numerous uses have been reported for all parts of the plant throughout its distribution area. The covering around the pollinium of pergularia daemia is sporopollenin in nature. Leaves are thin, broadly ovate and heartshaped 212 cm long, covered with soft hairs. The test organisms were bacillus subtilis, staphylococcus aureus, escherichia coli. The plant pergularia daemia has been traditionally used as laxative,antipyretic,expectorant and also used to treat infantile diarrhea and. Callus culture and plant regeneration from seedling explants.
The results can also be downloaded as a csv file unicode utf8 encoding see status, confidence level, source for definitions. The values are statistically significant at two levels p pdf, sign in to an existing. The study aimed to evaluate the effect of metformin and the combined activity of p. Asclepias daemia, cynanchum extensum name of pergularia in different languages. Pergularia daemia asclepiadaceae is a perennial herb growing widely along the road sides of india. It has been used in folk medicine for the treatment of liver disorders. The voucher specimen of pergularia daemia was parc202118. Structure and development of fruit wall ornamentations in. Ethanol induced gastric damage showed gross mucosal lesion, including long haemorrhage bands and petechial lesion. Petroleum ether and methanol extract of the leaf and stem were powder and used for the experimental work. Nature of covering around the aggregate of microspores in.
Pergularia daemia was collected from the southern parts of pudukkottai district, tamil nadu, india, and planted in the j. This page was last edited on 30 september 2018, at 14. Pergularia daemia herb uses, benefits, cures, side effects. It is homologous to the tapetal membrane investing the inner tange we use cookies to enhance your experience on our website. The determination was carried out using the densitometric absorbance mode. Plant details information about pergularia daemia plant. Decoction of the leaves is given to children as an anthelmintic, in doses not exceeding three tablespoonfuls. It is a waxy steroid and is transported in the blood plasma of all animals. Dec 30, 2012 callus cultures were established from seedling explants of pergularia daemia forsk chiov on murashige and skoog ms medium supplemented with different concentrations of auxins. Uses, benefits, cures, side effects, nutrients in pergularia daemia. Phytochemical analysis of pergularia daemia for its.
Phytochemical analysis of pergularia daemia for its bioactive. Impact of whole plant extract of pergularia daemia on. Analgesic and anti inflammatory activity of stem of. The separation was performed on silica gel 60 f254 hptlc plates with toluene. Analysis of some secondary metabolites, total phenolic, flavonoids, flavonols, and procyanidins, was performed using different solvents. Pergularia daemia, chemoadjuvant, rtpcr, western blotting, introduction oral cancer is a cancer that affects any part of the mouth, such as the jaw bone, oral muscles, the gums, lips, tongue, andor the cheek. List of various diseases cured by pergularia daemia.
Butanolic extract of roots analyzed with ir spectra revealed the presence of hydroxyl, alcoholic, and carboxylic groups and sugars units. Assessment of the antioxidant potential of pergularia daemia. K 3 1research scholar, department of biochemistry, bharathiyar university, coimbatore641046, tamilnadu. Then the extract was concentrated and the percentage 68 page 5 april 2016. Pergularia daemia, the trellisvine, is a hispid, perennial vine in the family apocynaceae, with an extensive range in the old world tropics and subtropics. The hydroalcoholic extracts of pergularia daemia haepd and terminalia catappa l. Leaf extracts vijaya packirisamy 1 and indumathi parameswaran 2 and vijayalakshmi. Pdf antibacterial activity of a novel quinone from the. Asclepediaceae, extract 50% alcohol was investigated for its antiurolithiatic and diuretic activity. Optimal callus developed from leaf explants on ms medium supplemented with 2,4d 2 mg l. Small disease free tender leaf were collected from 56 months grown plants, cut into 0. Pergularia daemia is a perennial twining herb, foulsmelling when bruised. It is the main sterol synthesized by animals small amounts are also synthesized in plants and fungi.
Earlier reports indicate various beneficial uses of the herb, validating it as a medicinal herb. It has been used traditionally to treat a number of ailments, it occurs from the malay peninsula to burma, sri lanka, afghanistan through arabia and egypt to central and southern africa. Antibacterial activity of 35 extracts at three different concentrations of various plant parts of strychnos nuxvomica linn. Oral administration of the alkaloidal fraction at a dose of 200mg kg. It is a perennial twining herb with hairy stem, it produces an irritating. Extract weight of residue % yield petroleumether 60800 35 gm 5% benzene 10 gm 1. By continuing to use our website, you are agreeing to our use of cookies.
Antifertility activity of pergularia daemia request pdf. Antifertility activity of the alkaloidal fraction of pergularia daemia since both the fractions of the c 2 h 5 oh extract at a dose of 200mg kg1 body weight inhibited the implantation of the fertilized ova, the activity of the alkaloidal fraction was compared with that of the steroidal fraction in terms of their effect on the oestrous cycle. The present study deals with the phytochemical examination and therapeutic importance of pergularia daemia. Studies on the hepatoprotective effect of acetone and ethanol sub fractions of ethanolic fraction obtained from total ethanol extract was carried out using carbon tetrachlorideinduced toxicity in primary cultured rat hepatocytes. Leaves to 10 x 8 cm, ovate, caudateacuminate, base deeply cordate. Jun 30, 2017 in this study, we investigated antiepileptogenic and neuroprotective effects of the aqueous extract of pergularia daemia roots pdr using in vivo and in vitro experimental models. Antiurolithiatic activity of wholeplant hydroalcoholic. Pergularia daemia is a perennial twinning herb that grows along the roadsides of india and tropical and subtropical regions in south asia, africa, and australia. Cholesterol exists in the outer layer of every cell in our body and has many functions. Nutritional composition and phytochemical, antioxidative. Pergularia daemia parc20211 and terminalia catappa was parc20142063. Pergularia daemia leaves were collected in august september 2012 from south poigainallur village in nagapattinam district of tamilnadu, india and the plant was taxonomically identified by dr. How pergularia daemia is effective for various diseases is listed in repertory format. Chiov is ornamented with large number of branched and unbranched soft spines.
The ethanol extract of pergularia daemia and its steroidal fraction are reported to have antifertility activity. The antibacterial activity of an extract from pergularia daemia leaves was tested against pathogenic bacteria. Hepatoprotective effect of extracts from pergularia daemia. Pergularia daemia plant has been documented for presence of presence of triterpenes, saponins cardenolides and alkaloids. The plantpergularia daemia asclepiadaceae7 known as veliparuthi in tamil, uttaravaruni in sanskrit and utranajutuka in hindi. Pdf invitro evaluation of hepatoprotective activity of. Oral squamous cell carcinoma is a major component of a diverse group of neoplasms often referred to as head and neck cancer.
The aim of this work is to study the hepatoprotective effect of crude ethanolic and aqueous extracts from the aerial parts of pergularia daemia. Department of agriculture agricultural research service. Pergularia daemia is a perennial twinning herb that grows along the roadsides of india and tropical and subtropical regions in south asia, africa, and australia pharmacological activities include antiinflammatory, hepatoprotective, anticancer, antidiabetic, antioxidant, antibacterial, antifungal, analgesic, antiinfertility and. Click below on a thumbnail map or name for species profiles. Crude extracts from a medicinal tunisian plant, pergularia tomentosa l. Adventitious shoots were regenerated 70% from the calli on ms medium. Names of pergularia daemia in various languages of the world are also given. Request pdf antifertility activity of pergularia daemia the ethanolic extract of pergularia daemia and its steroidal fraction were studied for antifertility activity. The diuretic activity of the different extracts at a dose of 400 mgkg was assessed orally in rats with furosemide as a standard drug using lipschitzs test. Diuretic potential of whole plant extracts of pergularia.
Antifertility activity of the alkaloidal fraction of. Assessment of the antioxidant potential of pergularia. The powder of pergularia daemia the powder of pergularia daemia extracted by using petroleum ether as a solvent by maintai till a color less solvent appears from siphon tube. The hydro alcohol extracts of pergularia daemia and. The plant pergularia daemia asclepiadaceae is known as uttaravaruni in sanskrit and utranajutuka in hindi.
Cholesterol is a fat lipid which is produced by the liver and is crucial for normal body functioning. Antiepileptogenic and neuroprotective effects of pergularia. The aqueous and ethanolic extracts obtained from aerial parts of pergularia. A mature spine consists of an epidermis enclosing parenchymatous ground tissue with vascular strands and laticifers. In this work we studied the alkaloidal fraction of the ethanol extract to observe its antifertility activity. Jayaraman, plant anatomy research centre, chennai, tamilnadu, india. Matured leaves of pergularia daemia and terminalia catappa red leaves were shade dried at room temperature and were powdered by using mechanical grinder. Frequent smoking andor alcohol consumption are two major risk factors for oral cancer. This finding supports its use for the treatment and management of cardiovascular diseases. In this study, we investigated antiepileptogenic and neuroprotective effects of the aqueous extract of pergularia daemia roots pdr using in vivo and in vitro experimental models.
A herbal formulation prepared from pergularia daemia, brachiaria eniciformis. Evaluation of pergularia daemia and metformin in the. It is a hispid perennial herb that grows along the roadsides of india and other tropical and subtropical regions. The board of trustees of the royal botanic gardens, kew. Modern research has shown the presence of a wide range of medically active compounds, especially glycosides. Stems bears milky juice and covered with longer stiff erect hairs 1mm. Female albino wistar rats 150 180 g were injected with testosterone propionate tp for the development pcos. Pergularia daemia forsk showed a dose dependent curative ratio compared to ulcer control groups. Antibacterial and phytochemical evaluation of pergularia.
Hypolipidemic activity of pergularia daemia leaves extract on. After 2 h of status epilepticus, mice were treated during the epileptogenesis. Pergularia is a genus of the botanical family apocynaceae. It develops from the epidermal and subepidermal ground tissue layers of the ovary wall. Hypolipidemic activity of pergularia daemia leaves extract. Usda, ars, germplasm resources information network.
Haetc were used for the gcms analysis and molecular docking with selective proteins. The plants were raised in pots containing mixture of soil and farmyard manure in the ratio of 1. The pcos induced rats were divided into two groups, one were treated with metformin and the other were treated. All structured data from the file and property namespaces is available under the creative commons cc0 license.
The word cholesterol comes from the greek word chole, meaning bile, and the greek word stereos, meaning solid, stiff. In in vivo studies, status epilepticus caused by pilocarpine injection triggers epileptogenesis which evolves during about 12 weeks. Pergularia daemia var daemia, vrugte, b, springbokvlakte. The aim of the present study was to investigate the in vitro antioxidant assays and in vivo non enzymatic antioxidant potential of aerial parts of pergularia daemia methanolic extract pdme on 7, 12dimethylbenzaanthracene dmba induced hamster buccal pouch hbp carcinogenesis. Pergularia daemia in the germplasm resources information network grin, u. Wo20121723a1 a herbal formulation to treat mastitis in. The plants database includes the following 1 species of pergularia.